Menu 1. what is bio-printing? 2. Advantages and disadvantage 3.The major component of bioprinting 4.Company and products 5.Development cost 6.Future use and Technology 7.How prevalent will the technology become? 8.Barriers to adoption
What is bio-printing?
It uses printing devices that deposit biological materials.
Bio-printing constructs 3D artificial tissues by computer devices.Bio-printing
technology is developed by Gabor Forgacs, a biophysicist from University of
Missouri in the US. Bioprinters can print complex 3D structures with the
combinations of “bioink” and “biopaper.” Today, bio-printing is still at
development stage and is used as scientific tools. In long-term, this
technology is expected to be used for creating replacement organs and human
tissues from raw biological materials.
human tissue by full body transplant
scientists to eliminate the wait list of organ transplants ·
survival rate of printed cells
high precise resolution
The replacement of molecules or cells within the
reconstructed organ is not sure about whether they can fit into a human body as
Large-scale construction increases the complexity associated
Printing capabilities of complicated tissues
The necessary specifications required for given printing
construction (for therapy design, need to be precise and specific)
The Major Components of Bio-printing
An organ is cut horizontally so that scientists can see an array of cells on the surface. The cells are then collected to make BioInk, which change the shape of cells to spheroids. Then the BioInk is placed inside the bio-printer. The spheroids are dropped into hydrogel, which acts as a placeholder. This step is repeated several times to make layers of spheroids which eventually form a 3D tissue.
Products and Company
1. The main company for this
technology is Organovo. This company focuses on the research and
development on bio printing.
2. NovoGen MMX Bioprinter™ is the
main machine that has been developed to meet challenges in biological research
in regards to bio printing.
3. The main
Bioprinter pioneer: Japanese scientist Makoto Nakamura’s modified inkjet
4. In 2008, he
created a working bio printer that prints out bio tubing similar to a blood
Japanese scientist Makoto Nakamura
1. A bio printer
requires huge informational contents of human tissues to print organs.
2. Organovo spends about
$15.2 million of funding to further research bio printing and requires
financial help of investors and donors as well.
3. Information that is
needed for bio-printing is expensive. For example, 1Pb of human
tissue contents is approximately $71,680.
4. Companies need to
spend additional fees on hiring the experts who can operate the bio printer.
Future Use and Technology
1. It could be utilized to create
entire living organs such as heart, liver and kidneys
2. Creation of functional human
beings, which can be printed on demand and reach maturity in few weeks.
3. Newly developed drugs can be
tested out on manufactured cells than on animals and humans. It will lead to a
huge reduction in cost and time.
4. Situ bio printing works by
imprinting cells directly onto human body.
How Prevalent Will the Technology Become?
The technology will be universally accepted by hospitals because bio
printing will be used to print complete organs that are ready for
In 20 years, bio printing will be mainstream and accepted.
Barriers to Adoption
1. Bio-printing conflicts with moralities
and cultural and religious beliefs.
2. BIo-printing will increase life span of
people on resource- limited planet earth
3. Increase in world population.
4. “Fountain of Youth”, people will not
grow older and die naturally.